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*Search "Rothwell PE" on PubMed for most recent updates

Brandner DD, Retzlaff CL, Kocharian A, Stieve BJ, Mashal MA, Mermelstein PG & Rothwell PE. Neuroligin-3 in dopaminergic circuits promotes behavioural and neurobiological adaptations to chronic morphine exposure. Addiction Biology 28:e13247. PMID: 36577719.

Lefevre EM, Gauthier EA, Bystrom LL, Scheunemann J & Rothwell PE.Differential Patterns of Synaptic Plasticity in the Nucleus Accumbens Caused by Continuous and Interrupted Morphine Exposure. The Journal of Neuroscience 43, 308-318. PMID: 36396404.

Retzlaff CL & Rothwell PE. Characterization and mu opioid receptor sensitivity of neuropeptide Y interneurons in the mouse nucleus accumbens (2022). Neuropharmacology, 218:109212. PMIC: 35963449.

Trieu BH, Remmers BC, Toddes C, Brandner DD, Lefevre EM, Kocharian A, Retzlaff CL, Dick RM, Mashal MA, Gauthier EA, Xie W, Zhang Y, More SS & Rothwell PE (2022). Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid. Science 375, 1177-1182. PMID: 35201898

Toddes C, Lefevre EM, Brandner DD, Zugschwert L & Rothwell PE (2021). μ-Opioid Receptor (Oprm1) Copy Number Influences Nucleus Accumbens Microcircuitry and Reciprocal Social Behaviors. The Journal of Neuroscience 41, 7965-7977. PMID: 34301826


Borland JM, Kim E, Swanson SP, Rothwell PE, Mermelstein PG & Meisel RL (2020). Effect of Aggressive Experience in Female Syrian Hamsters on Glutamate Receptor Expression in the Nucleus Accumbens. Frontiers in Behavioral Neuroscience. PMID: 33328919

Lefevre EM, Pisansky MT, Toddes C, Baruffaldi F, Pravetoni M, Tian L, Kono TJ & Rothwell PE (2020). Interruption of Continuous Opioid Exposure Exacerbates Drug-Evoked Adaptations in the Mesolimbic Dopamine System. Neuropsychopharmacology 45, 1781-1792. PMID: 32079024

- Commentary by Cahill: "Opioid dose regimen shapes mesolimbic adaptations"

Corkrum M, Covelo A, Lines J, Bellocchio L, Pisansky M, Loke K, Quintana R, Rothwell PE, Lujan R, Marsicano G, Martin ED, Thomas MJ, Kofuji P & Araque A (2020). Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity. Neuron 105, 1036-1047. PMID: 31954621

Pisansky MT, Lefevre EM, Retzlaff CL, Trieu BH, Leipold DW & Rothwell PE (2019). Nucleus Accumbens Fast-Spiking Interneurons Constrain Impulsive Action. Biological Psychiatry 86, 836-847. PMID: 31471038

- Commentary by Corbit, Gittis & Ahmari: "A Model of Restraint: Nucleus Accumbens Fast-Spiking Interneurons Inhibit Unwanted Actions"

Corkrum M, Rothwell PE, Thomas MJ, Kofuji P & Araque A.Opioid-Mediated Astrocyte-Neuron Signaling in the Nucleus Accumbens. Cells 8: 586. PMID: 31207909

Gokce O, Stanley GM, Treutlein B, Neff NF, Camp JG, Malenka RC, Rothwell PE, Fuccillo MV, Südhof TC, Quake SR (2016). Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq. Cell Reports 16, 1126-1137. PMID: 27425622

Rothwell PE (2016). Autism spectrum disorders and drug addiction: Common pathways, common molecules, distinct disorders? Frontiers in Neuroscience. PMID: 26903789

Fuccillo MV, Rothwell PE & Malenka RC (2016). From synapses to behavior: what rodent models can tell us about neuropsychiatric disease. Biological Psychiatry 79, 4-6. PMID: 26616432

Rothwell PE*, Hayton SJ*, Sun GL, Fuccillo MV, Lim BK & Malenka RC (2015). Input- and output-specific regulation of serial order performance by corticostriatal circuits. Neuron  88, 345-356 (*Co-first authors). PMID: 26494279

Fuccillo MV, Földy C, Gökçe O, Rothwell PE, Sun G, Malenka RC & Südhof TC (2015). Single-cell mRNA profiling reveals cell-type specific expression of neurexin isoforms. Neuron 87, 326-340. PMID: 26182417

Rothwell PE*, Fuccillo MV*, Maxeiner S, Hayton SJ, Gökçe O, Lim BK, Fowler SC, Malenka RC & Südhof TC (2014). Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors. Cell 158, 198-212 (*Co-first authors). PMID: 24995986

Rothwell PE & Lammel S (2013). Illuminating the opponent process: cocaine effects on habenulomesencephalic circuitry. Journal of Neuroscience 33, 13935-13937. PMID: 23986229

Lim BK, Huang KW, Grueter BA, Rothwell PE & Malenka RC (2012). Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbens. Nature 487, 183-189. PMID: 22785313

Grueter BA, Rothwell PE & Malenka RC (2012). Integrating synaptic plasticity and striatal circuit function in addiction. Current Opinion in Neurobiology 22, 545-551. PMID: 22000687

Rothwell PE, Thomas MJ & Gewirtz JC (2012). Protracted manifestations of acute dependence after a single morphine exposure. Psychopharmacology 219, 991-998. PMID: 21833504

Rothwell PE, Kourrich S & Thomas MJ (2011). Environmental novelty causes stress-like adaptations at nucleus accumbens synapses: Implications for studying addiction-related plasticity. Neuropharmacology 61, 1152-1159. PMID: 21315090

Radke AK, Rothwell PE & Gewirtz JC (2011). An anatomical basis for opponent process mechanisms of opiate withdrawal. Journal of Neuroscience 31, 7533-7539. PMID: 21593338

Rothwell PE, Kourrich S & Thomas MJ (2011). Synaptic adaptations in the nucleus accumbens caused by experiences linked to relapse. Biological Psychiatry 69, 1124-1126. PMID: 21329910

Rothwell PE, Gewirtz JC & Thomas MJ (2010). Episodic withdrawal promotes psychomotor sensitization to morphine. Neuropsychopharmacology 35, 2579-2589. PMID: 20811341

Rothwell PE (2010). Parsing spontaneous and evoked neurotransmission on both sides of the synapse. Journal of Neuroscience 30, 6480-6481. PMID: 20463211

Overland AC, Kitto KF, Chabot-Dore A-J, Rothwell PE, Fairbanks CA, Stone LS & Wilcox GL (2009). Protein kinase C mediates the synergistic interaction between agonists acting at alpha-2-adrenergic and delta-opioid receptors in spinal cord. Journal of Neuroscience 29, 13264-13273. PMID: 19846714

Rothwell PE, Thomas MJ & Gewirtz JC (2009). Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposure. Neuropsychopharmacology 34, 2285-2295. PMID: 19494807

Harris AC, Rothwell PE & Gewirtz JC (2008). Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesia. Psychopharmacology 196, 649-660. PMID: 18026718

Kourrich S, Rothwell PE, Klug JR & Thomas MJ (2007). Cocaine experience controls bidirectional synaptic plasticity in the nucleus accumbens. Journal of Neuroscience 27, 7921-7928. PMID: 17652583

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